DISCONTINUATION OF NON-VITAMIN K ANTAGONIST ORAL ANTICOAGULANTS IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION: A POPULATION-BASED COHORT STUDY USING PRIMARY CARE DATA FROM THE HEALTH IMPROVEMENT NETWORK IN THE UK

Objective To determine discontinuation rates, patterns of use and predictors of discontinuation of non-vitamin K antagonist oral anticoagulants (NOACs) among patients with non-valvular atrial fibrillation (NVAF) in the first year of therapy.Design Population-based cohort study.Setting UK primary care.Population 11 481 patients with NVAF and a first

IODP Expedition 357 utilized seabed drills for the Body Silk first time in the history of the ocean drilling program, with the aim of collecting intact sequences of shallow mantle core from the Atlantis Massif to examine serpentinization processes and the deep biosphere.This novel drilling approach required the development of a new remote seafloor

Abstract Background When promoting public health measures, such as reducing smoking, there are many different approaches, for example providing information, imposing legal restrictions, taxing products, and changing cultures.By analogy with evidence-based medicine, different approaches to campaigning for health promotion can be compared by obtainin

Quantum computers may solve some computing tasks more efficiently than classical com- puters, but to do so requires the design of appropriate quantum circuits.However, it is hard to design even simple quantum programs.Recent results have shown that NUTRI C COMPLEX deep learning augmented search has the potential to discover good circuits for a prob

This study investigates the pragmatic transfer in English request realizations made by EFL learners, i.e.the proficient learners.The subjects were students of an DAMIANA English Study Program who obtained TOEFL-like scores of at least 450.The data were collected by means of DCT-questionnaires and Role-plays.The results show that the subjects realiz